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Respironics PR System One DS650 REMstar BiPAP Pro with humidifier
Model: DS650HS

Respironics PR System One DS650 REMstar BiPAP Pro with humidifier
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This product is discontinued. Please check its upgraded version BiPAP Auto 60 series.

This bundle includes the PR BiPAP Pro with Bi-Flex and Humidifier.

The PR System One REMstar BiPAP Pro with humidifier is a wide pressure range (4-25cm), and advanced sleep therapy device. The System One BiPAP Pro features an easily adjustable ramp, BiFlex comfort technologies, automatic altitude adjustment, a data card for expanded data storage and convenient data sharing, the device also comes with a versatile power supply. The System One BiPAP Pro is a bi-level auto adjusting device, that dynamically adapts to your inhalation and exhalation levels providing you with constant and optimum pressure, for a comfortable and uninterrupted nights sleep. It features proprietary resistance control technologies such as automatic adjustment to mask types with its innovative device-mask tracking system. The BiPAP Pro also features advance event detection, response, and reporting, helping the device to automatically adjust to advanced OSA (obstructive sleep apnea) and non-OSA events, ensuring that you get personalized and the best therapy possible.

Flex Family Technologies - The BiPAP AUTO features Bi-FLEX+ for Superior Comfort and a More Natural Breathing Experience

The proprietary Flex Family Technologies are clinically proven technologies that improve conventional pressure therapy, providing the user constantly ideal levels of comfort leading to increased compliance. The PR System One REMstar BiPAP Pro also features the innovative Bi-Flex technology that efficiently tracks and analyses every breathe, automatically adjusting to deliver pressure relief as needed during inhalation and exhalation for a more natural breathing experience.

Enhanced System One Humidity Control with Dry Box Technology

Heated humidity plays a huge role in comfort and compliance. This model of PR System One REMstar Pro Auto is packaged with a System One Heated Humidifier to deliver excellent management of humidity, maintaining it at optimal levels all the time. It is effective in minimizing rainout, and spontaneously adjusts to surrounding temperature, and relative humidity, irrespective of seasonal conditions. It also features enhanced therapy flow for additional comfort. The proprietary Dry Box technology included in this package also conveniently separates the water source from the internal electronic assembly of the device to eliminate any risk of spillage and consequent water damage.

System One Resistance Control

Proprietary System One Resistance Control, provides the user exceptional comfort and versatility. With the System One Resistance Control, the user is ensured that the device and mask work together, delivering ideal and comfortable pressure constantly. The System One BiPAP automatically adjusts for varying resistance, making it virtually compatible with different mask types, resulting in excellent synchronicity between mask and device for optimal pressure at all times, guaranteeing not only maximum comfort, but also improves compliance to therapy.

Highly Effective Advanced Event Detection, Reporting & Response for Superior Monitoring of Therapy

Respironics System One BiPAP Pro is capable of advance tracking and monitoring of common OSA events such as hypopneas, respiratory effort related arousal, flow limitation, leaks, and snores. Non classic OSA symptoms including clear airway and obstructed apneas, as well as periodic breathing are also easily detected. The device automatically adjusts therapy levels for the appropriate response providing optimum therapy at all times.

System One Humidity Control for Superior Comfort and Enhanced Therapy

The System One Humidity Control, delivers consistent humidity to the mask, and evaluates room humidity, room temperature, and air flow, and spontaneously adjusts to ideal humidity levels throughout use, for consistent comfort during sleep. System One Humidity Control is also capable of reducing rainout. An easy to use dial is also available for adjusting mask humidity. Controlling mask humidity output, aside from setting humidity temperature, provides a comfortable nights sleep.

Dry Box Technology For Safety

The sealed water chamber and Dry Box Technology eliminates the risk of water leakage and consequent damage of the sensitive internal electronics of the device. The Dry Box technology is virtually assures a leak free device. Even if the water chamber is full, it can be tilted and even turned upside down without any leakage into the device. In any event that water escapes the chamber, the Dry Box is an assurance that it will not enter the device itself.

No Refunds, Returns or Exchanges on Open Products Except for Warranty/RMA process or Mask Assurance.

HCPCS CPAP Code(s): E0470 (BiPAP), E0562(humidifier)

Product Specifications


Bi-level Spontaneous Bi-Flex

Pressure Range:

IPAP: 3 cm H2O to 20 cm H2O
EPAP: 3 cm H2O to 20 cm H2O

Ramp Time :

0 to 45 min. (5-min. increments)

Ramp Activation:

Unlimited number of ramps per night

Starting Ramp Pressure:

3 cm H2O to EPAP level

BiPAP Dimensions:

11.4" L x 7.0" W x 5.5" H


5.75 lbs (2.6 kg)


Reusable Pollen, Optional Ultra Fine


On-board keypad

Therapy Memory

6 months @ 3 usage sessions/day; 7 days in-depth data analysis. Date, time, duration at pressure, patient event histograms, short-term detailed events, long-term trends, FOSQ tests and SmartCard


Pressure Setting, Data/Time of each use, duration at Pressure

Compliance Meter

LCD: Total Operation Time and Time at Pressure

Data DS Card:


Pressure Relief on Exhale:

Yes, Flex Family

Auto Altitude Compensation:


Electrical Requirements:

100 240 VAC, 12 DC

Battery Operation:



Integrated Heated Humidifier


2-Year Manufacturer Warranty

DC Power:

Direct-connect cord

  • Respironics PR System one REMStar BiPAP Pro CPAP Machine with Bi-Flex
  • Travel Bag
  • System One Heated Humidifier
  • User Manual
  • Performance Tubing only
  • Power Adapter (auto adaptive 100v-240v AC)
  • Free Filters for 3 years (only from Respshoppe)
  • Smart Card
  • by Deborah B Date Added: Friday 22 June, 2012
    This was the second unit i purchased. Much better then my first one, and very impressed with its options and functions!

    Rating: 5 of 5 Stars! [5 of 5 Stars!]
    Displaying 1 to 1 (of 1 reviews) Result Pages:  1